Microwave assisted extraction for PFAS analysis

Environmental laboratory

Microwave assisted extraction for PFAS analysis

18 Sep, 2025

Many laboratories measure PFAS in a variety of different matrices where the sample preparation stage can often be the time limiting step that can take up to 80% of the total analysis time. An alternative method that is currently widely used for sample preparation for organic pollutant analysis is Microwave Assisted Extraction (MAE) that can now be employed for PFAS samples using a new rotor specifically developed for this application.

Using the Milestone EthosX MAE system from Analytix coupled with the 44-place rotor provides an EPA 1633 compliant solution and offers high throughput with PFAS free disposable vials that eliminates any cleaning stage. The samples are kept in the same vial throughout the process thereby minimising contamination, eliminating possible carryover, and reducing sample extraction time by 70%. 

Advanced sensors in the EthosX MAE system deliver precise temperature control throughout the extraction process with uniform conditions across all positions that guarantees consistent and reproducible results with excellent recoveries vs. alternative techniques.

The new application note describes the full procedure for extraction with sample preparation stages and the microwave system method. 

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