Separate out isobaric interferences to achieve new levels of precision and accuracy with unique MS/MS technology

Environmental laboratory

Separate out isobaric interferences to achieve new levels of precision and accuracy with unique MS/MS technology

30 Aug, 2022

Published over 4 years ago. See the latest and most current information on Environmental laboratory.

Thermo Fisher Scientific Pte Ltd Chromatography & Mass Spectrometry Division
1 min read

The new Thermo Scientific™ Neoma™ MS/MS MC-ICP-MS is built upon the robust Thermo Scientific Neoma MC-ICP-MS platform but goes an extra step of combining market-leading sensitivity and precision with ultimate isotope selectivity with the patented MS/MS technology. 

The unique pre-cell mass filter allows only a small mass range to enter the collision/reaction cell optimising the reaction pathways within the collision/reaction cell and dramatically improving abundance sensitivity. 

In geological research, boron isotope analysis of carbonate samples via LA-ICP-MS has previously been challenged by elevated 10B baselines due to the interferences from scattered Ca4+ ions. The pre-cell mass filter of Neoma MS/MS MC-ICP-MS eliminates this problem by filtering out Ca ions before isotopic separation. This means that measured boron isotope ratios of carbonate samples are accurate and do not require a secondary matrix correction. 

By eliminating the interference from scattered Ca ions, the Neoma MS/MS MC-ICP-MS allows for accurate boron isotope analysis of carbonate samples, precluding the requirement for well-matched standards. This should allow researchers to investigate a wider range of samples and provide confidence in the accuracy of the boron isotope ratio. 

The Neoma MS/MS MC-ICP-MS platform offers technology that users can trust: · 

  • Extended dynamic range 
  • Excellent abundance sensitivity 
  • Extended choice with 24 amplifier array  
  • Enhanced variable detector array 

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