• Analysis of Aminoglycosides Using the Alexys 100 LC-EC System

Environmental Laboratory

Analysis of Aminoglycosides Using the Alexys 100 LC-EC System

Oct 29 2007

With the release of the ALEXYS 100 LC-EC system in 2004, Antec Leyden (The Netherlands) became a supplier of system solutions. Dedicated solutions are now available for environmental, clinical and pharmaceutical applications based on this integrated LC system with electrochemical detection.
The aminoglycosides are a broad-spectrum antibiotics used against gram-positive and gram-negative bacillary infections in both clinical and veterinary medicine. We developed a simple and sensitive analysis method
for the determination of Neomycin, Tobramycin and Gentamicin in pharmaceutical preparations, using reversedphase Liquid Chromatography (LC) and Pulsed Amperometric Detection (PAD) on a gold working electrode
after post-column addition of sodium hydroxide. For the analysis of Kanamycin and Amikacin another system solution is available based on ion exchange chromatography with PAD.

Digital Edition

AET 28.2 April/May 2024

May 2024

Business News - Teledyne Marine expands with the acquisition of Valeport - Signal partners with gas analysis experts in Korea Air Monitoring - Continuous Fine Particulate Emission Monitor...

View all digital editions

Events

CISILE 2024

May 29 2024 Beijing, China

KIOSH

May 29 2024 Astana, Kazakhstan

ASMS Conference

Jun 02 2024 Anaheim, CA, USA

MSS 2024

Jun 03 2024 Portoroz, Slovenia & online

View all events