Additional Patent Notices of Allowance for Flash Chromatography Technology

W. R. Grace & Co. (USA) announced today that the U.S. Patent and Trademark Office has granted three additional Notices of Allowance related to the company’s Reveleris flash chromatography system. The benefits derived from these allowed claims enable streamlined purification of new chemical/biological entities for drug discovery.

These notices describe actively controlling the split flow, using chromaphoric solvents, and collecting fractions based on a wavelength range during flash chromatography. These techniques streamline purification of new chemical/biological entities during drug discovery by increasing recovery, improving reliability and simplifying instrument operation.

Grace previously announced receipt of a patent for the use of Evaporative Light Scattering Detection (ELSD) with flash chromatography, a key part of the Reveleris flash chromatography system.