Fast and high-resolution LC-MS separation with Ascentis® Express PFAS HPLC columns

PFAS (Per- and poly-fluoroalkyl substances) are persistent, man-made organic compounds, widely found in the environment. Recent awareness has brought attention to the toxicity of these substances. The U.S. Food and Drug Administration (FDA) and the U.S. Environmental Protection Agency (EPA) have initiated actions against PFAS. For determination of PFASs, liquid chromatography–mass spectrometry (LC-MS) is a commonly used technique.

Merck’s new Ascentis® Express PFAS HPLC column, with its Fused-Core® technology and a particle size of 2.7 µm, delivers fast and high-resolution separations with excellent selectivity, peak shape, and necessary retention to perform in EPA methods 537.1, 533 and 8327.

Key benefits of Ascentis® Express PFAS columns include:

• 2.7 µm Fused-Core® particle for reliable and high efficiency separations and lower column back pressure compared to sub-2 µm particles
• Excellent suitability for MS detection
• Application-related Lot analysis and single column performance testing
• Pressure limit: 600 bar

Ascentis® Express PFAS HPLC columns enable precise MS results The Ascentis® Express PFAS HPLC column is designed for the separation of novel and legacy short chain and long chain PFAS compounds containing branched and linear isomers, whilst adhering to EPA methodology requirements. Furthermore, a specific PFAS delay column prevents background PFAS contamination from interfering with the sample results in quantitative LC-MS methods.

Discover Merck’s complete solution for PFAS analysis at SigmaAldrich.com/PFAS