• SPE cartridges provide superb levels of purity and consistency for PFAS and other environmental samples

PFAS Analysis

SPE cartridges provide superb levels of purity and consistency for PFAS and other environmental samples

Jun 11 2024

EPA Method 1633 provides a highly efficient and precise method for the determination and quantification of per- and polyfluoroalkyl substances (PFAS) in samples that contain complex matrices. This method is widely recognized for its ability to accurately detect PFAS compounds, which are often present in very low concentrations and are difficult to isolate due to the complexity of the sample matrices.  The method is particularly important given the increasing concerns over the environmental and health impacts of PFAS, which are persistent and bio-accumulative.

InertSep is a renowned line of solid-phase extraction (SPE) cartridges that stand out in the market for their exceptional purity, consistency, and overall quality. These attributes make InertSep cartridges a preferred choice among analysts seeking reliable and reproducible results.  Within the InertSep product line, InertSep WAX FF and GCB Stacked SPE cartridges are specifically optimized for PFAS analyses, providing fast flow rates and efficient cleanup from various sample types such as aqueous solutions, soil, food, and other complex matrices. The high recoveries ensure that significant portions of the PFAS present in the samples are successfully extracted, while the cleanup efficiencies minimize the presence of interfering substances that could affect the accuracy of the analysis.

Graphite Carbon Black (GCB) is a material known for its superior ability to remove impurities thus providing a clean sample for subsequent analysis.  InertSep GCB is an excellent choice for liquid chromatography-mass spectrometry (LC/MS) analysis, where the efficiency of sample cleanup is critical in obtaining accurate and reliable results. The excellent cleanup efficiency of InertSep GCB ensures that the samples are free from contaminants that could interfere with the detection and quantification of PFAS, thereby enhancing the overall reliability and sensitivity of the analysis.

In summary, EPA Method 1633, in combination with high-quality InertSep Stacked SPE cartridges and an InertSustain AQ-C18 HPLC column, provides a robust and effective solution for the analysis of PFAS in complex matrices. The fast flow rates and superior cleanup efficiencies of these cartridges make them indispensable for analysts working to detect and quantify PFAS in environmental and food samples, ensuring accurate and reliable results in the face of challenging samples.


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